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Dynamic Polymeric Membrane Structures for Separation of Proteins

Gordon G. Wallace

Chee O. Too

Intelligent Polymer Research Institute, University of Wollongong, NSW 2522, Australia

Novel dynamic polymeric membrane structures have been successfully prepared. These membranes have the necessary strength and pore size for use in electrochemically facilitated transport and separation of proteins. The transport of proteins can be electrochemically initiated and sustained or hindered when required. A high purity of human serum albumin (HSA) can be separated from a mixture containing equimolar concentrations of HSA and Myoglobin. Quartz crystal microbalance studies show that, in these cases of transport and separation, the overriding controlling factor was electrochemical control, although polymer/protein interactions do affect the transport fluxes.

Journal of Intelligent Material Systems and Structures, Vol. 8, No. 12, 1052-1058 (1997)
DOI: 10.1177/1045389X9700801206


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